Search on: THYMIDYLATE SYNTHASE 
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Descriptor English:   Thymidylate Synthase 
Descriptor Spanish:   Timidilato Sintasa 
Descriptor Portuguese:   Timidilato Sintase 
Synonyms English:   Thymidylate Synthetase
Synthase, Thymidylate
Synthetase, Thymidylate  
Tree Number:   D08.811.913.555.500.862
Definition English:   An enzyme of the transferase class that catalyzes the reaction 5,10-methylenetetrahydrofolate and dUMP to dihydrofolate and dTMP in the synthesis of thymidine triphosphate. (From Dorland, 27th ed) EC 2.1.1.45. 
History Note English:   98; see METHYLTRANSFERASES 1975-85 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   14327 
Unique Identifier:   D013940 

Occurrence in VHL:
 

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